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References

1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page-304.

2. Adam M Henrie, James J Nawarskas, and Joe R Anderson. Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636095/

3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf

4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36

5. Central Drugs Standard Control Organization. Tadalafil tablet 20 mg (Additional Indication). [Revised in November 2009]. Tadalafil 10mg/20mg Tablets. [Revised in September 2003] [Accessed on November 08th, 2023]https://cdscoonline.gov.in/CDSCO/Drugs

ClexMax® (cinespaceMCB) [Internet].https://cdscoonline.in/CDSCO/Tadalafil

CNS Generics Limited.https://www.nskmc.com/product/556/cns Generics

AppIONViewe® (cinespaceMCB) [Internet].https://ns.broadonic.com/app/View/CNS Genericsaiapostakorte® (cinespaceMCB) [Internet].https://ns.broadonic.in/app/Access-Cinespace

Anna Sombreros, Oxford University, Bitterly, Bomer, Wir, Voldweill, and Bailey edicology book deal.https://www.annonsombreros.com/product/556/aiapostakorte

aiapostakorte-OSE(R) (cinespaceMCB) [Internet].

aiapostakorte-OSE(R) (cinespaceMCB) [Internet] [Accessed on November 08th, 2023]

aiapostakorte-totopoiese(R) (cinespaceMCB) [Internet].https://www.annonsombreros.com/product/556/aiapostakorte-totopoiese

aiapostakorte-totopoiese-OSE(R) (cinespaceMCB) [Internet].https://ns.broadonic.in/app/Access-View/View-CNS Generics

eCinespace® (EMC) [Revised in September 2009]. [Revised in November 2009] [Accessed on November 08th, 2023]https://www.leeford.in/product/556/e-cinespace

https://www.nskmc.com/product/556/e-cinespace

AppIONe® (cinespaceMCB) [Internet].

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Definition

G. Drug-Drug Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, possibly altering its effectiveness or increasing the risk of side effects. While here are some drug-food interactions that may be noticed:

  1. : Grapefruit can increase the levels of tadalafil by inhibiting an enzyme called- phosphodiesterase-5 (PDE5). This enzyme is responsible of breaking down blood pressure-lowering chemicals. Avoid grapefruit and grapefruit juice while taking Cialis.
  2. : Though not a direct interaction, combining Cialis with grapefruit or grapefruit juice might worsen side effects like headaches or increase tadalafil availability in your blood.
  3. : While tadalafil may be taken with Cialis, avoiding it without a high-fat meal might delay its onset of action.

C.

Cialis 20 Mg In Pakistan

Cialis (Tadalafil) is a medication primarily used to treat erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). It works by relaxing blood vessels in the lungs, thereby enhancing blood flow to the lungs. It is a prescription medication and is available in Pakistan only as a generic. It is also available over-the-counter and is widely available in most cities in Pakistan.

Cialis 20 Mg is a medication typically used to treat erectile dysfunction and pulmonary arterial hypertension. It works by increasing blood flow to the penis, helping to achieve and maintain an erection. However, it is also used to treat benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension (PAH). It is available both in Pakistan and the USA.

Key Features

Cialis 20 Mg is a medication that is effective for both men and women. It is a prescription medication that is available over-the-counter (OTC) or prescription in Pakistan. It contains the active ingredient tadalafil, which is also available as a generic drug.

Indications for Use

Cialis 20 Mg is prescribed to treat erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). It helps improve blood flow to the penis, leading to a firm and long-lasting erection.

It is also used to treat benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension (PAH).

Precautions and Contraindications

It is crucial to discuss with your doctor before taking Cialis 20 Mg. You should always consult with your doctor before taking this medication.

It is not recommended for women or children. It may cause unwanted side effects in some individuals. It is also not recommended for women or children.

Dosage and Administration

Cialis 20 Mg is typically taken 30 minutes to 4 hours before sexual activity. It is available in both liquid and tablet forms. It is generally taken once a day. It is not recommended for daily use. You should always follow the instructions provided by your healthcare provider or pharmacist.

Important Information

It is essential to discuss with your doctor before using Cialis 20 Mg.

Side Effects

The most common side effects of Cialis 20 Mg are headaches, indigestion, back pain, muscle pain, and nasal congestion. These side effects are usually mild and temporary. However, if they persist or worsen, it is essential to contact your doctor.

Important Precautions and Contraindications

It is essential to discuss with your doctor before taking Cialis 20 Mg.

Warnings and Precautions

If you have ever had a heart attack, stroke, or have suffered a heart attack, it is essential to discuss with your doctor before using Cialis 20 Mg.

Nicknamed “The Weekender Pill”,Tadalafil is the generic version of Cialis™. It lasts up to 36 hours and the reason some prefer Tadalafil over Sildenafil, which typically last up to 8 hours. Please select your preferred dosage and number of pills.

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* We can ship up to 30 pills at a time. For example, if you order 120 pills, you will get four shipments of 30 pills.

Health Questionnaire Required:

For your first order with us, after placing an order, you will be prompted to upload your ID and submit our health questionnaire, soour physician canreview your basic health information,in order to mail prescription medications. You will not need to do this for refill orders.

Disclaimer:This is not medical advice. You and our physician will determine if (and potentially how) you should take Tadalafil. Please consult with your physician if you have any further questions.For more information on Tadalafil,.

Looking for Tadalafil tablets?.

You and our physician will seek advice from your physician with whom you have been prescribed Tadalafil for Erectile Dysfunction (ED) problems at your direction.

For your first order with us, you will be prompted to upload your ID and submit our health questionnaire, soyour order will be filled. We willreview your basic health information, in order to mailprescription medications. You will not, however, need to do this for refill orders.

Tadalafil Tablets 10 & 20

Take Tadalafil as prescribed by your physician. The typical starting dose is 10mg, which, if taken as prescribed, you may get four tablets of 5mg (5 pills) of Tadalafil per day. Please ensure that you have at least one health question you haveiculty or discomfort at least one hour before having sex. Do not take a higher dose of Tadalafil, Tadalafil, or Cialis than 10 & 20mg tablets per day unless your doctor has told you to.

Note:HIP-HIP Code:

The above information may containaneaar, Sexual Health, Intersex, BPH, Individuals with Benign Prostatic Hyperplasia (BPH), and others.

Tadalafil Tablets USP & HGH USP

Hormones may affect the way other medications work, and some may affect the way other medications work for you. Usually, you should take your medications exactly as they appear on your health questionnaire. However, this may vary from prescription to prescription so be sure to ask your doctor or pharmacist any questions you have about any other medications you are taking or about your health condition.

All medications except Tadalafil are available by prescription only. If you are pregnant, might become pregnant, or are breast-feeding, you should not take Tadalafil or its products. If you have any questions about Tadalafil or its products,,, or the.

As with all medications, here are some precautions:

  • Tadalafil and other ED medications may cause serious side effects. If you experience any serious or unexpected side effects, stop taking your medications and seek emergency medical attention immediately.

4 Generic Cialis Tablets – 20 Trillion Brand name Treats Erectile Dysfunction

Tadalafil is the active ingredient of the brand Cialis. It belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. These tablets help maintain blood flow to the penis during sexual stimulation by relaxing the blood vessels in the penis. This results in increased blood flow and enables the user to achieve and maintain an erection.

4 Generic Cialis Tablets – 20 Trillion Brand Name Treats Erectile Dysfunction

This medication helps to maintain a healthy erection by inhibiting the enzyme PDE5, which is responsible for inhibiting the phosphodiesterase type 5 (PDE5) enzyme. By doing so, it prolongs the duration of sexual intercourse and improves the overall sexual experience.

It works by relaxing blood vessels in the penis, allowing increased blood flow during sexual stimulation. This results in the treatment of erectile dysfunction in men. These tablets help men with erectile dysfunction maintain an erection long enough for sexual intercourse. The treatment is available both orally and by injection.

Tadalafil is available in various strengths, including 5mg, 10mg, 20mg, and 40mg tablets. The recommended starting dose is 5mg, which should be taken about 30 minutes before sexual activity. The tablets can be taken on an empty stomach or with food. The medication is usually taken on an empty stomach. The tablets are taken approximately one hour before sexual activity.

It is important to note that Tadalafil should only be taken as prescribed by a healthcare professional. If you have any concerns about your treatment or sexual activity, please consult your doctor or pharmacist.

Cialis 5mg 20mg

The medication is available both orally and by injection.

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